Getting Started Pharmacy calculations are very important for prescribing, especially in regards to renal function and pediatric dosing. This assignment will focus on calculating renal function and med

1. Using the Cockcroft -Gau lt equation, calculate creatinine clear ance for the following patient: 70 year old female, 5’6” tall, 150 lb, SCr = 1.2 mg/dL. Round your answer to the nearest 1 mL/min . 2. A 1-year -old male weighing 28 lbs is diagnosed with acute otitis media and will be treated with amoxicillin/clavulanate (Augmentin ®). The recommended dosing is 90 mg/kg/day , divided every 12 hours . How many mL of 600 mg/5 mL would be given with each dose ? Round your answer to the nearest 0.5 mL. 3. A 7-year -old female weighing 55 lbs presents with a severe asthma exacerbation and will be treated with prednisolone (Orapred ®). Recommended dosing is 1 mg/kg/day in 2 divided doses. How many milligrams would be prescribed per dose ? Round you r answer to the nearest mg. 4. A 10 -year -old female weighing 8 0 lbs presents with a urinary tract infection and will be treated with sulfamethoxazole/trimethoprim (Bactrim ®). Dosing for this medication is typically based on the trimethoprim component.

Suspension is available as 200 mg of sulfamethoxazole and 40 mg of trimethoprim in every 5 mL. Dosing for this indication is trimethoprim 8 mg/kg/day divided every 12 hours. How many milliliters of sulfamethoxazole would be given with each dose ? Round your answer to the nearest 0.5 mL. 5. A 6-year -old male weighing 50 lbs presents complaining of a sore throat and has a positive rapid strep test. He will be treated with amoxicillin (Amoxil ®) with dosing of 50 mg/kg/day. How many milligrams/day would be prescribed? Round your answer to the nearest 5 mg . 6. From question #5 - how many mL would this be (using 400 mg/5 mL concentration)? Round your answer to the nearest 0.5 mL. 7. A 2 month old weighing 9 lbs presents with erosive esophagitis . This will be treated with ranitidine (Zantac ®) 10 mg/kg/day in 2 divided doses. Ranitidine comes as a 15 mg/mL concentration. How many milliliters would be recommended for each dose ? Round your answer to the nearest 0.1 mL. 8. From question #7 – how m any mL would be needed for a 30 day supply? Round your answer to the nearest 5 mL but be sure to give adequate supply. 9. A mother of a 4 year old weighing 30 lbs calls your office asking for dosing recommendations for ibuprofen (Motrin ®) for a fever. Recommended dosing is 5 -10 mg/kg every 6 -8 hours as needed. Ibuprofen suspension concentration is 100 mg/5 mL. What range , in milliliters, would be appropriate for this patient for each dose ? Round your answer to the nearest 0.5 mL. 10. From question # 9 – the mother decides that she would rather use acetaminophen (Tylenol ®). Dosing recommendation is 10 -15 mg/kg/dose and the suspension concentration is 160 mg/5 mL. What range, in milliliters, would be appropriate for this patient for each dose ? Round you r answer to the nearest 0.1 mL.