would you please edit my assignment. I am trying to do a Brochure .

Brochure

OXBRYTA

Belong to a drug class called

Hemoglobin S polymerization

Inhibitors

-Mechanism of Action

This meds used to treat Sickle cell

Disease in Adults and children’s older

Then 12 years.

• Someone who suffer Sickle cell

Have a abnormal form of hemoglobin S.

-Oxbryta work by targeting hemoglobin S

To inhibit the process of sickling

Drug Administration and dosage

1500 mg once per day to treat sickle cell disease

Take with or without food

Drug Interactions

Avoid taking Oxbryta with

CYP3A4 inhibitors such as

Clarithromycin, erythromycin, and ritonavir

It can cause Oxbryta toxicity

Special Considerations/ side effect

This drug may cause a serious allergic reaction

And side effect such as diarrhea, headache,

Abdominal pain, and fatigue

Contraindications

Avoid grapefruit, it can

Increase toxicity.

Lab’s test/ interference

Oxyberta can affect Certain lab test that measure hemoglobin levels. This drug may interfere with measurement of Hb by high performance liquid chromatography.

Patient education Consideration

• It is very important to read the information on bottle before taking Oxbryta

• This is not recommended to consume this drug when has an allergic reaction

• Oxbryta is not recommended when one receives any exchange transfusion.

• It not advisable to change the dose and not follow the reequipment provided by your physician.

• This drug can be taken with or without food as long as you follow the prescribed instructions.

• This drug should not be administered together with anti-diarrheal meds and any other calcium supplements.

Side effect

The most known side effects of this medication are: headache, fever, Nausea, Rush, tiredness, stomachs pains and vomiting

= it is very recommended to check in with the doctors for more advice regarding possible side effects.

More consideration

• Pregnancy women have an increased adverse effect outcomes for fetus and mother. they have a high risk of obtaining maternal mortality and eclampsia.

• There is an increased risk of low birth weight and preterm delivery for the fetus. It is important to consider all this before administering medication to pregnant women.

Patient education is very crucial, especially when the medication side effects are concerned. Before taking the medication, the provider should be aware of any medical problem, including liver problem.

• It is highly recommended patient to inform healthcare providers of any medication taking including vitamins, herbal supplements, and drugs.

Nursing Implications

• Healthcare provider need to monitor the psychological status and effects and suicidal though during the initial steps of therapy