Review Chapter 5 Searching the Evidence, Chapter 6 Evidence Appraisal Research, and Chapter 7 Evidence Appraisal Nonresearch in the Johns Hopkins Evidence-based Practice for Nurses and Healthcare Prof

Johns Hopkins Evidence-Based Practice Model for Nursing and Healthcare Professionals


Hierarchy of Evidence Guide

Appendix D


Evidence Level

Types of Evidence

Research Evidence

(Appendix E)

Level I

  • Experimental study, randomized controlled trial (RCT)

  • Explanatory mixed methods design that includes only a Level I quaNtitative study

  • Systematic review of RCTs, with or without meta-analysis 

Level II

  • Quasi-experimental study

  • Explanatory mixed methods design that includes only a Level II quaNtitative study

  • Systematic review of a combination of RCTs and quasi-experimental studies, or quasi-experimental studies only, with or without meta-analysis 

Level III


  • Nonexperimental study

  • Systematic review of a combination of RCTs, quasi-experimental and nonexperimental studies, or nonexperimental studies only, with or without meta-analysis. 

  • Exploratory, convergent, or multiphasic mixed methods studies

  • Explanatory mixed methods design that includes only a Level III quaNtitative study

  • QuaLitative study

  • Systematic review of quaLitative studies with or without meta-synthesis

Nonresearch Evidence

(Appendix F)

Level IV

Opinion of respected authorities and/or nationally recognized expert committees or consensus panels based on scientific evidence. Includes:

  • Clinical practice guidelines

  • Consensus panels/position statements

Level V

Based on experiential and non-research evidence. Includes:

  • Scoping reviews

  • Integrative reviews

  • Literature reviews

  • Quality improvement, program or financial evaluation

  • Case reports

  • Opinion of nationally recognized expert(s) based on experiential evidence

Note: Refer to the appropriate Evidence Appraisal Tool (Research [Appendix E] or Nonresearch [Appendix F]) to determine quality ratings.

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