Please look at attachment and follow directions please do not use google and label things yourself. You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini

Chapter 5 Hands-On Lab: Tissue Histology Instructions

In this exercise, you will be gaining “hands-on” experience with histology slides through a web-based resource called HistologyGuide.org. You will be navigating through a wide variety of tissue sections at various magnifications just as you would if you were using a physical microscope. For each tissue listed, you will be asked to locate and label a specific set of structures.

To document your work, please follow these steps:

  • Locate the specific tissue/structures at the specified magnification.

  • Take a screenshot of the image by clicking on the down arrow next to “Select View” in the top-right of the microscope view.

  • Label the required structures on the image.

  • Click the blue box to insert your saved image file (or insert image and then label).

  • Save the completed document as a .pdf and upload it into the appropriate MyCourses Assignment Folder.


Important Note on Academic Honesty

All labelled images must represent your own original work and may not be copied from another student or images found online. Each image should include your initials in the corner using the same digital pen/tool used for labelling structures.


Epithelial Tissue
  1. Simple Squamous Epithelium

On the Histology Guide website, navigate to Slide Box > Chapter 2 Epithelium > Simple Squamous Epithelium > MH 016 @ 40x magnification. NOTE: This slide contains 4 different tissues. Using the far-right tissue of this set, find one of the many round structures known as renal corpuscles (described with a figure in the gray description box to the right of the Histology Guide screen).

Take a screenshot of the tissue at 40x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. lumen

  2. squamous epithelial cells

  3. apical surface

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 1


  1. Simple Cuboidal Epithelium

In the Slide Box, navigate to Chapter 2 Epithelium > Simple Cuboidal Epithelium > MH 016 @ 40x magnification. NOTE: This slide contains 4 different tissues. Use the far-right tissue on this slide.

Take a screenshot of the tissue at 40x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. lumen

  1. cuboidal epithelial cells

  2. apical surface

  3. basal surface

  4. basement membrane

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 2


  1. Simple Columnar Epithelium

In the Slide Box, navigate to Chapter 2 Epithelium > Simple Columnar Epithelium > MHS 219 @ 40x magnification.

Take a screenshot of the tissue at 40x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. lumen

  1. columnar epithelial cells

  2. apical surface

  3. basement membrane

  4. goblet cells

  5. microvilli


  1. Stratified Squamous Epithelium

In the Slide Box, navigate to Ch.2 Epithelium > Stratified Squamous Epithelium > MH109 @ 10x magnification.

Take a screenshot of the tissue at 10x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. lumen

  1. squamous epithelial cells

  2. apical surface

  3. basal surface

  4. basement membrane

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 3



  1. Pseudostratified Columnar Epithelium

In the Slide Box, navigate to Ch.2 Epithelium > Pseudostratified Columnar Epithelium > MHS 222 @ 40x magnification. NOTE: Use the far-right tissue sample for the best view.

Take a screenshot of the tissue at 40x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. lumen

  1. columnar epithelial cells

  2. Goblet cells

  3. apical surface

  4. basement membrane

  5. cilia

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 4


Connective Tissue
  1. Areolar Connective Tissue

On the Histology Guide website, navigate to Slide Box > Ch.3 Connective Tissue > Connective Tissue > Fig 024 Types of Connective Tissue > Loose Areolar Connective Tissue @ 20x magnification

Take a screenshot of the tissue at 20x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. collagen fibers

  1. elastic fibers

  2. fibroblast

  3. ground substance

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 5


  1. Adipose Tissue

In the Slide Box, navigate to Ch.3 Connective Tissue > Adipocytes > MHS 213 Lymph Nodes @ 40x magnification.

Take a screenshot of the tissue at 40x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. adipocyte

  1. adipocyte nucleus

  2. fat droplet

  3. ground substance

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 6


  1. Reticular Connective Tissue

In the Slide Box, navigate to Organ Systems > Ch.10 Lymphoid System > Lymph Node > MH 076-077-078 Lymph Node @ 20x magnification.

Take a screenshot of the tissue at 20x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. reticular fibers

  1. leukocytes

  2. ground substance

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 7


  1. Dense Regular Connective Tissue

In the Slide Box, navigate to Ch.3 Connective Tissue > Dense Regular Connective Tissue > MH 029a Tendon @ 40x magnification.

Take a screenshot of the tissue at 40x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. collagen fibers

  1. fibroblast

  2. ground substance

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 8


  1. Dense Irregular Connective Tissue

In the Slide Box, navigate to Ch.3 Connective Tissue > Dense Irregular Connective Tissue > MH 091 Thick Skin @ 40x magnification. NOTE: This is the skin. Dense irregular CT is only found in the deeper layers of the skin. To find the connective tissue, you must navigate away from the apical surface where the epithelial tissue is located.

Take a screenshot of the tissue at 40x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. collagen fibers

  1. fibroblast

  2. ground substance

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 9


Additional Connective Tissues
  1. Bone

On the Histology Guide website, navigate to Slide Box > Chapter 5 Cartilage and Bone > Compact Bone > MHS 202 Ground Bone. Using the drop-down menu at the top of the slide, select Osteon #1.

Take a screenshot of the tissue at this magnification. Label each structure listed, and insert your labelled image in the box below.

  1. osteon

  2. lacunae

  3. bone matrix (referred to as lamellae in the gray box to the right)


Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 10




  1. Cartilage

On the Histology Guide website, navigate to Slide Box > Chapter 5 Cartilage and Bone > Hyaline Cartilage > MH136 Trachea @ 10x magnification. Locate the top tissue.

Take a screenshot of the tissue at 10x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. chondrocyte

  1. matrix

Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 11



  1. Blood

In the Slide Box, navigate to Ch. 7 Peripheral Blood > Blood Cells > MH 033hr Blood Smear (use the 2nd one in the list). Using the drop-down menu at the top of the slide, select Neutrophil #1.

Take a screenshot of the tissue at this magnification. Label each structure listed, and insert your labelled image in the box below.

  1. red blood cells

  1. white blood cell (neutrophil)


Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 12

[INSERT PHOTO BOX HERE]



Muscle Tissue
  1. Skeletal Muscle

On the Histology Guide website, navigate to Slide Box > Chapter 4 Muscle > Skeletal Muscle > MH 055ahr (longitudinal section) @ 60x magnification.

Take a screenshot of the tissue at 60x with all of the following structures in view. Label each structure listed, and insert your labelled image in the box below.

  1. skeletal muscle cell

  2. nucleus

  3. Striations


Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 13


Nervous Tissue
  1. Neuron

In the Slide Box, navigate to Ch.6 Nervous Tissue > Spinal Cord > UCSF 163 Spinal Cord. Using the drop-down menu at the top of the slide, select Motor Neuron.

Take a screenshot of the tissue at this magnification. Label each structure listed, and insert your labelled image in the box below.

  1. neuron cell body

  2. nucleus


Please look at attachment and follow directions  please do not use google and label things yourself.  You will be using this website https://www.histologyguide.org/ In this exercise, you will be gaini 14


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