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QUESTION
"Null alleles" (mutant genes) produce no protein product; this is a genetic change. However, epigenetically silenced genes also produce no protein...
“Null alleles” (mutant genes) produce no protein product; this is a genetic change. However, epigenetically silenced genes also produce no protein product. How does one distinguish experimentally whether a gene has been silenced by mutation or been silenced epigenetically?
