Answered You can hire a professional tutor to get the answer.
QUESTION
6. (8 pts) Formation of acetyl-CoA from pyruvic acid (an alpha-keto acid) involves a thiamine diphosphate (TPP)-dependent oxidative decarboxylation
6. (8 pts) Formation of acetyl-CoA from pyruvic acid (an alpha-keto acid) involves a thiamine diphosphate (TPP)-dependent oxidative decarboxylation process that also involves an enzyme-bound lipoic acid. Given the structures of TPP and enzyme-bound lipoic acid below, please show detailed mechanism for the formation of acetyl-CoA from pyruvic acid.
