a mutation in DNA generates a UGA stop codon in the middle of the RNA coding for a particular protein.

a mutation in DNA generates a UGA stop codon in the middle of the RNA coding for a particular protein. A second mutation in the cell leads to a single nucleotide change in a tRNA that allows the correct translation of the protein. The altered tRNA translates the UGA as tryptophan. What nucleotide change has probably occurred in the mutant tRNA molecule? What consequences would the presence of such a mutant tRNA have for the translation of the normal genes in this cell?