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Carboxylic acids and their derivatives are important parts of many of the medicines used daily by many people. Similarly to what we did in Hands-On...
Carboxylic acids and their derivatives are important parts of many of the medicines used daily by many people. Similarly to what we did in Hands-On Chemistry 16.1, let's take a look at some of the top 200 drugs of 2015, many of which you have probably heard about and see what functional groups are pre- sent. You will need to have an internet connection to fully carry out this activity.
a.)Let's begin by looking at an antibiotic you have surely heard of—penicillin. What you may not know is that there are two commonly used forms: penicillin G and penicillin V. Look up the structures of these, draw their line structure, and identify all the carboxylic acid derived functional groups present. How do the two penicillins differ from one another? How are they the same? From a treatment standpoint, what is each used for?
b.) As of September 2014, the top 10 selling prescription drugs by trade name were as follows:
1. Crestor 2. Synthroid