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Complete 5 pages APA formatted article: Autism and Dementia. The most profound neurodevelopmental disorder is autism. This disorder is characterized by impaired communication (verbal and non-verbal),
Complete 5 pages APA formatted article: Autism and Dementia. The most profound neurodevelopmental disorder is autism. This disorder is characterized by impaired communication (verbal and non-verbal), limited social interaction, and repetitive and restricted behavior. In childhood, the signs are observed at the age of one to two years. However, children with autism may achieve developmental milestones just like normal children and later regress.
Causes of Autism
In most cases, autism is highly caused by heredity, genetic susceptibility, and environmental factors. In a few circumstances, autism is associated with birth defect-causing agents. However, the environmental cause of autism is an issue that is subject to controversy since the vaccine hypothesis has been disapproved in many scientific studies. Autism affects the brain's information processing ability by altering how synapses and nerve cells organize and connect. .
Despite numerous extensive research on autism's neurobiology of autism, the heterogeneity of the main cause of autism remains unknown. The Intense World Syndrome has introduced the hypothesis that autism is neurobiology grounded. Additionally, the hypothesis further explains that it works upward from the molecular, the cellular, and circuit levels until it reaches the potential cognitive levels (Calleo, 2008). This hypothesis obtains its foundations from the experiments on the valproic acids of the rat model of autism. The experiments explored the alterations across the cellular, molecular, circuit, synaptic, and behavioral models where pregnant rats were given a high Valproic acid intake.
The study showed that the rats had a higher risk of getting autistic offsprings. The hypothesis was postulated to human beings. In this case, the synaptic dysfunction may result from mutations where the nerve cell adhesion to the synapses disrupts the synaptic pathway. According to past research on the replacement of genes in mice, autistic symptoms are closely associated with later developmental stages that depend on activity within the synapses and activity-dependent changes. Additionally, congenital disability causing agents related to high risk of autism are observed within the first eight weeks after conception. As a result, autism tends to occur in the early development stages of a child (Calleo, 2008).
