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Consider yourself to be very frustrated from all the mice in your house that eat all the candies on your table at night.
Consider yourself to be very frustrated from all the mice in your house that eat all the candies on your table at night.
a) Which populations of cells in the brain change their activity when a normal mouse becomes hungry?
b) Design an experiment to test how you will find sweet sensing neurons in the mouse's brain.
c) Assume you are able to find these sweet sensing neurons. You decide to make a transgenic line that finds sweet taste to be bitter and unpleasant. What type of receptors will you find on them? What receptors would you want your transgenic mice's sweet neurons to express?
d) Assume you are able to create the transgenic mouse that finds sweet candies bitter. What new neuronal mechanism might be at play here?
