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Describe in detail the glycoproteins on the surface of the lymphocytes and the tumor cells that are responsible for shutting the lymphocytes down
Describe in detail the glycoproteins on the surface of the lymphocytes and the tumor cells that are responsible for shutting the lymphocytes down (what kind of proteins they are, their structures, etc.) and the mechanism of this inactivation (including signaling pathways). How do the therapeutic antibodies function to allow activation of the lymphocytes—do they all bind to the same epitopes? (30pts)