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Formulate a PICOT for the following case and write 5 steps of EBM Female patient with ulcers suffered from osteoarthritis in her knee ,her son want

Formulate a PICOT for the following case and write 5 steps of EBM 

Female patient with ulcers suffered from osteoarthritis in her knee ,her son want her to start on celecoxib because he heard they cause Gi complications

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