Hello, I am looking for someone to write an essay on Jaundice as a Presenting Complaint for Acute Myeloid Leukamia. It needs to be at least 2000 words.Download file to see previous pages... These repo

Hello, I am looking for someone to write an essay on Jaundice as a Presenting Complaint for Acute Myeloid Leukamia. It needs to be at least 2000 words.

These reports are important, because they analyse the latest techniques for treating specific types of AML, and these reports have proved to be promising, with significant survival rates, especially compared to the survival rates of those with conventional therapies. Discussion 1. What is AML, How Common is It, The General Symptoms and the Subtypes Acute myeloid leukemia (AML) is considered to be the most common kinds of acute leukemia in adults. That said, its incidence is still relatively rare, accounting for just over 1% of all cancer deaths per year (Jemal et al., 2002). In 2005, the National Cancer Institute reported that there were just under 12,000 new cases of AML reported, and 10,000 deaths from the disease (Resource4Leukemia.com). The disease is rare in those under the age of 40 years old, and generally strikes those over the age of 60. It is also more common in men than in women. This cancer is signified by having an abnormal cells in the person’s bone marrow. These cells replace the healthy bone marrow tissue, as they grow so rapidly. Because of this, the bone marrow stops working correctly, and, since the bone marrow is responsible for fighting infections, the person with AML becomes more prone to infections. They also have an increased risk for bleeding, as the healthy blood cells decrease and are replaced by the abnormal cells (A.D.A.M Medical Encyclopedia, 2010). The French-American-British (FAB) classification divides AML into eight different subgroups. They are listed as follows, as well as the percentage of all AML patients who have each of the subgroups listed (Bennett et al., 1976): M0 minimally differentiated acute myeloblastic leukemia 5% M1 acute myeloblastic leukemia, without maturation 15% M2 acute myeloblastic leukemia, with granulocytic maturation t(8.21)(q22.q22), t(6.9) 25% M3 promyelocytic, or acute promyelocytic leukemia (APL) t(15.17) 10% M4 acute myelomonocytic leukemia inv(16)(p13q22), del(16q) 20% M4eo myelomonocytic together with bone marrow eosinophilia inv(16), t(16.16) 5% M5 acute monoblastic leukemia (M5a) or acute monocytic leukemia (M5b) del (11q), t(9.11), t(11.19) 10% M6 acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) 5% M7 acute megakaryoblastic leukemia t(1.22) 5% 2. Misdiagnosis of AML, and the consequences of this Because AML presents with symptoms which are shared with other, more common and much less lethal, diseases, it is often misdiagnosed. The symptoms include fever, shortness of breath, fatigue, weight loss, increased bruising, bone and joint pain and persistent infections. Unfortunately, because these symptoms are the same as other diseases, such as the flu or the common cold, doctors often do not diagnose it properly unless they are specifically looking for this disease (Resource4Leukemia.com). According to Huq et al. (2005), a misdiagnosis of this disease results in increased mortality. They reported on a case of an African-American male who presented with symptoms consistent with pneumonia, including a fever, cough and back pain. His lab results showed evidence of leukocytosis and anemia, and he was treated for pneumonia with a course of azithromycin.