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Hello, I am looking for someone to write an essay on Treatment of Multiple Sclerosis. It needs to be at least 2750 words.This paper illustrates that Borazanci define multiple sclerosis (MS) as “an i
Hello, I am looking for someone to write an essay on Treatment of Multiple Sclerosis. It needs to be at least 2750 words.
This paper illustrates that Borazanci define multiple sclerosis (MS) as “an inflammatory demyelinating and degenerative disease of the human central nervous system (CNS)”. In the U.S.A about 500,000 individuals are affected by this disease, which targets young individuals, and is a significant reason for neurological deficits among the young adult population of the nation. In spite of several and continuous efforts to remove the enigma in the etiology of MS, its cause remains elusive, and so too a cure for the disease. Till about two decades back no MS specific treatments were available, but currently several MS specific treatments are available. Though the exact cause of MS is still clouded in mystery, its pathogenesis is linked to an abnormal immune response to CNS antigens, break down of the blood-brain barrier, and transendothelial migration from the peripheral circulation to the CNS by activated leukocytes, chemokines, and cytokines. In the active form of the disease apparently there is continuing inflammatory and neurodegenerative processes occurring in the environment of the CNS. The trigger for the preliminary attack of MS still remains to be uncovered, but it is hypothesized that genetic and environmental factors are involved in the development of the disease. Experimental studies on mice have led to the surmise that autoreactive T cells are activated in the peripheral immune system against the CNS antigens like myelin basic protein and proteolipid protein, and then cross the blood-brain barrier to enter the CNS.