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Hi, need to submit a 1500 words paper on the topic Mechanistic Basis of Acupuncture.

Hi, need to submit a 1500 words paper on the topic Mechanistic Basis of Acupuncture. &nbsp.It also reduces nausea associated with pregnancy (Kaptchuk 374-383). It is not fully known as to what is the mechanism of action behind these effects. Various theories have been put forward by scientists. As early as 1974, a research group from Peking&nbsp.studied the mechanism on rabbits. They found that infusion of cerebrospinal fluid from a rabbit that had undergone acupuncture into a naive rabbit resulted in significant increase in the pain threshold of the recipient rabbit.&nbsp. So the researchers&nbsp.thought that substances that are released from the central nervous system mediated acupuncture-induced analgesia.&nbsp. Later, several types of research pointed to the stimulation of secretion of endogenous morphine-like substances called endorphins (Kaptchuk 374-383). The studies&nbsp.proposed that these endorphins act on the opiate receptor sites and inhibit the transmission of pain signals. The evidence to support this action was that endorphin levels in blood and cerebrospinal fluid increased in response to acupuncture and naloxone and other opiate receptor antagonists blocked this effect. Also, loss of opiate receptors in genetically altered mice resulted in suppression of this effect. Some other studies have shown that acupuncture stimulates type 3 small afferent fibers within muscle tissue (Stux 187: 209). These fibers which are connected to the hypothalamus-pituitary axis act both locally through the spinal cord, and systemically through the release of neurochemicals. The local and distal pain-suppressing effects of acupuncture is dependent upon electrical stimulation of the acupuncture needle. Different frequency and intensity of electrical stimulation determines whether the effect is local, i.e.

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