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QUESTION

How are liver disease, low blood pressure and high ammonia levels related?

The job of the live is to detoxify ammonia and break down certain mediators (like estrogen) that cause vasodialation. In Chronic Liver Disease and Cirrhosis this ability lost. Ammonia levels rise resulting in brain damage and the increase in levels of vasodialatos cause vasodialation and low BP which inturn can result in high output cardiac failure (the most common cause of death in these patients)

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