How does vaccine distribution relate to key operations and supply chain management questions including: quality management, new product development

How does vaccine distribution relate to key operations and supply chain management questions including: quality management, new product development and forecasting?Could more vaccine be made available if the government or patients simply paid more money for it? What are the pluses and minuses of producing extra at an increased cost?How should the government and producers balance safety – i.e. carefully assessing the vaccine so that few unintended consequences occur – versus speed of getting the vaccine to patients?