Look at thegene sequence below : Which of these mutations do you think will not cause any consequences?Which are more drastic?

Original Sequence 

(note that spacing and color is to aid in identifying codons and mutations, respectively)

AUG AAC CAG GGG UGG UGU CGA CCA AUA GUG CCC UCU UUU UAC GGU UAC UUG CCG CGG UAG

Mutations

1

AUG AAC CAG GGG UGG UGU CGA CCA AUA GUG CCCACU UUU UAC GGU UAC UUG CCG CGG UAG

2

AUG AAC CAG GGG UGG GUG UCG ACC AAU AGU GCC CUC UUU UUA CGG UUA CUU GCC GCG GUA G

3

AUG AAC CAG GGG UGG UGU CGA CCA AUA GUG CCC UCU UUU UAG GGU UAC UUG CCG CGG UAG

4

AUG AAC CAG GGG UGG UGU AGA CCA AUA GUG CCC UCU UUU UAC GGU UAC UUG CCG CGG UAG

5

AUG AAC CAG GGG UGA UGU CGA CCA AUA GUG CCC UCU UUU UAC GGU UAC UUG CCG CGG UAG