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QUESTION

Mannitol is filtered in the kidney as freely as water, but renal tubules lack the mechanism for reabsorbing mannitol from the ultrafiltrate and...

Mannitol is filtered in the kidney as freely as water, but renal tubules lack the mechanism for reabsorbing mannitol from the ultrafiltrate and returning it to the blood. You would expect the following in the patient described in problem 9:a) frequent trips to the bathroom because mannitol is a diuretic, an osmotic diuretic in particular,b) complaints of thirst because the infused mannitol is strongly hyper-osmotic to the patients plasma,c) renal excretion as the only mechanism for clearing mannitol from the blood,d) the renal excretion of water that has been pulled out of the brain.

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