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Marker genes (MGs) are essential tools in genetic transformation process. Marker genes are generally grouped as either selectable marker genes or reporter genes. Selectable marker genes are genes, whi
Marker genes (MGs) are essential tools in genetic transformation process. Marker genes are generally grouped as either selectable marker genes or reporter genes. Selectable marker genes are genes, which enable the selection/recovery of transformed cells/tissues from untransformed tissues in the growth media containing selecting agent (usually an antibiotic). Positive selectable marker genes (SMGs) are used in genetic transformation to allow only transgenic cells (which occur at very low frequency) to grow and develop and are necessary for efficient transformation. Negative SMGs confer a selective disadvantage to the cells that express them, and have several uses in both basic and applied research. Reporter genes (RGs) make it possible to easily screen cells or tissues for their expression
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