Multinational, Cross-functional teams You are the manager of a team with multiple cultures and nationalities. How do you manage this team

Multinational, Cross-functional teams 

You are the manager of a team with multiple cultures and nationalities.  How do you manage this team effectively?  How do you keep this team on task?  What warning signs of possible problems might you look for?

Now also imagine that some of these people are remote employees (either domestically or internationally remote).  What special considerations would you have to consider?