Mutation of the Q in a protein to an R (to make protein mutation) produces a change in delta G of binding with an absolute magnitude of 3 kcal/mol.

Mutation of the Q in a protein to an R (to make protein mutation) produces a change in delta G of binding with an absolute magnitude of 3 kcal/mol. What is the new Kd for the protein mutation-ligand complex? And how does this new Kd compare to the Kd for the wild-type protein-ligand complex?