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Not more than 5 H-bond donors (OH or NH) Not more than 10 H-bond acceptors (O or N) MW less than 500 g/mol What is the rational for the Rule of Five?...

Not more than 5 H-bond donors (OH or NH) Not more than 10 H-bond acceptors (O or N) MW less than 500 g/mol What is the rational for the Rule of Five?

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