Please, answer the questions for the following major cell cycle7cell death regulators, which are also involved in many cancer types. 1) RAS 2) MYC 3) p53 4) pRB Questions : a) protein's funct

Please, answer the questions for the following major cell cycle7cell death regulators, which are also involved in many cancer types.

1) RAS

2) MYC

3) p53

4) pRB

Questions :

a) protein's function (is it a transcription factor);

b) regulators (does it have bound partners?, is it monomeric);

c) how is the protein affecting cell cycle progression in normal cells? in cancer cells? (flow diagrams are welcome);

d) is this protein target for cancer therapy development;

e) In which kind of cancer cells it is mutant? What kind of mutations are common?