Please help me in describing the shift in the Roman Empire that created Byzantium in the East and what would eventually become Europe in the West.

Please help me in describing the shift in the Roman Empire that created Byzantium in the East and what would eventually become Europe in the West. Help explain the impact of this political, religious, and social split on the art produced in these regions in this era. Please provide examples of particular works of art or architecture to help me illustrate the points.