RESUHS Variables in the Equation B Step 1a Age 0.032 High_risk -0.401 Female -1 .176 Hispanic -0.252 Constant -1 .815 SE.016 0.417 0.398 0.434 1.056...

For the scenario presented below, answer the following:

1. What is the research question?
2. Using the table in the results section, answer the research question.
3. Interpret the difference in risk for 10 years in age, being designated high risk, male, and Hispanic in terms of statistical and clinical significance.

Aim: To develop an appropriate strategy to identify the patients who need upper endoscopy to assess for gastric cancer and its precursor lesions.

Methods: Consecutive procedures performed for these indications at our center between March 2010 and March 2013 were identified and individually reviewed to identify patient age, ethnicity, sex and the endoscopic/pathologic diagnosis. Consecutive proThe Clinical Outcomes Research Initiative (CORI) indications associated with gastric neoplasia were defined and characterized as high versus low risk. High risk indications included epigastric pain, weight loss etc. Low risk indications included dyspepsia, reflux, etc. Other predictors included age, gender, and ethnicity. These variables were included in a logistic regression model to assess their affect on well differentiated adenocarcinoma. Analyses were performed in SPSS V24.0; α = 0.05.   

Data coding:

Age in years

High_risk 0 = No; 1 = Yes

Female 0 = No; 1 = Yes

Hispanic 0 = No; 1 = Yes

differentiation 1 'Well differentiated' 0 'Poorly differentiated'