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SCA1 (spinocerebellar ataxia 1) is a familial genetic disease, describe the symptoms of the SCA1 disease.
A. SCA1 (spinocerebellar ataxia 1) is a familial genetic disease, describe the symptoms of the SCA1 disease.
B. In regards to the pedigree analysis chart, Explain how to read the chart by indicating what the squares and circles represent and what is the difference between filled and hollow shapes.
C. Assuming that the disease is caused by the mutation of one single gene, is this mutation recessive or dominant? Are the affected individuals more likely to be heterozygous or homozygous for this mutation? Is the disease affecting equally men and women? Please explain how these conclusions are supported by the pedigree.
