The naturally occurring compound urea, CO(NH2)2, was first synthesized by Friedrich Wohler in Germany in 1828 by heating ammonium cyanate.

The naturally occurring compound urea, CO(NH2)2, was first synthesized by Friedrich Wohler in Germany in 1828 by heating ammonium cyanate. This synthesis was a significant event because it was the first time that an organic compound had been produced from an inorganic substance. Urea may also be made by the reaction of carbon dioxide and ammonia.CO2(g) + 2 NH3(g) CO(NH2)2(s) + H2O(g)What volumes of CO2 and NH3 at 200 atm and 409.°C are needed to produce 2.8 kg of urea, assuming the reaction goes to completion?