The reaction of hemoglobin and oxygen is complicated. Explain some of this relationship in regards to the Hb-O2 saturation curves and why breathing...

The reaction of hemoglobin and oxygen is complicated. Explain some of this relationship in regards to the Hb-O2 saturation curves and why breathing at altitude is more difficult and CO2's role. (mention affinity for O2/CO2 and factors affecting the right shift)Answer in paragraph form and restate the question.