True or false: in aerobic organisms, all of the ATP that can be produced through glucose catabolism in the absence of O 2 comes from glycolysis. True...

1. True or false: in aerobic organisms, all of the ATP that can be produced through glucose catabolism in the absence of O2 comes from glycolysis.
2.  True
3.  False

0.5 points  

1. Which of the following pathways DOES NOT require O2?
2. Glycolysis
3. Pyruvate oxidation
4. The Citric Acid Cycle
5. Electron transport system
6. All of the above
7. None of the above

0.5 points  

1. Which of the following lists major reactants for the Light-dependent reactions?
2. Sunlight, H2O, CO2
3. Sunlight, ADP, NADP+, H2O, O2
4. Sunlight, ADP, NADP+, H2O
5. Sunlight, ATP, NADPH, O2

0.5 points  

1. How are the Light-dependent reactions of photosynthesis similar to the electron transport system in aerobic metabolism?
2. They both involve generation of a proton gradient that is harnessed to produce ATP.
3. Reduced coenzymes donate their electrons to the electron transport system, which harnesses the energy to produce a proton gradient.
4. They both use O2 as the final electron acceptor.
5. All of the above.

0.5 points  

1. The major carbohydrate-derived reactant of fermentation is ____; and during fermentation this compound is _____.
2. Lactate; oxidized
3. Ethanol; oxidized
4. Pyruvate; reduced
5. Citric acid; reduced

0.5 points  

1. Phosphofructokinase (PFK-1) is one of the most regulated enzymes in metabolism. Which of the following would be expected to be an allosteric activator of PFK-1?
2. AMP
3. Acetyl CoA
4. Citric acid
5. Pyruvate

0.5 points  

1. In the 1930's 2,4-dinitrophenol (DNP; shown below) was introduced to the market as a diet drug. DNP is a chemiosmotic "uncoupler" just like uncoupling protein (UCP) in brown fat. Uncouplers make the inner mitochondrial membrane permeable to protons (H+), causing them to flow down their concentration gradient without going through F0 and thereby bypassing the F1 ATP Synthase. As a result, the mitochondria fails to produce ATP when it breaks down glucose. DNP causes protons (H+) to flow:
2. From the intermembrane space to the cytoplasm.
3. From the intermembrane space into the mitochondrial matrix.
4. From the cytoplasm to the intermembrane space.
5. From the mitochondrial matrix to the intermembrane space.

0.5 points  

1. DNP was a very effective diet aid introduced in the 1930's, but it was nearly immediately taken off the market after several users died of acute hyperthermia (overheating). Why would DNP cause hyperthermia?
2. Individuals taking it would have the sensation of increased energy and would therefore become extremely physically active, increasing their body temperature.
3. The energy resulting from the increased metabolic rate would be released as heat.
4. Protons flowing down their concentration gradient is an exergonic process, the energy from which, when not captured by ATP Synthase, is released as heat.
5. Rapid oxidation of NADH and FADH2 would be uncoupled from proton transport and the energy from these reactions would be released as heat.

0.5 points  

1. Assuming O2 is available, in which of the following structures would you expect to see the highest pH?
2. The intermembrane space of the mitochondria
3. The mitochondrial matrix
4. The cytoplasm

0.5 points  

10

Assuming O2 is available, in which of the following structures would you expect to see the lowest pH?

The intermembrane space of the mitochondria

The mitochondrial matrix

The cytoplasm