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Two arrestin genes ( -arrestin 1 and 2) have been characterized and are expressed ubiquitously. Over the past several years, the development of...
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Two arrestin genes (β -arrestin 1 and 2) have been characterized and are expressed ubiquitously. Over the past several years, the development of knockout mice in which the genes for β-arrestin 1 and 2 have been inactivated have greatly aided the study of the physiological and cellular roles of these multifunctional proteins. To better understand the role of β-arrestin 1 and 2 in the desentitization of the b2-AR small interfering RNA (RNAi) were used to specifically suppress the expression of β arrestin 1 or 2 or both. The results are shown in the figure below.What does this figure show in term of specificity of the two siRNA molecules (β–arr1 and β -arr2)?