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What is pluto minimum distance from earth?
With due consideration of the high inclination ##17.2^o## of Pluto's orbital plane to our ecliptic, the least lower bound for the minimum Earth-Pluto distance is 4.29 B km = 2.66 B miles, nearly.
I have used NASA Planetary Fact Sheet data.
Pluto : Perihelion = 4.436 billion (B) km and orbital inclination to Earth's orbital plane = ##17.2^o##. Earth : Aphelion: 0.1521 B km.
For least possible Earth-Pluto distance,,in (E) - Sun (S) - Pluto (P) ##triangleESP##, SE = Earth aphelion, SP = Pluto perihelion and ##angleESP= max 17.2^o##
So, least ##EP = sqrt(SP^2+SE^2-2XSEXSPXcosangleESP)##. , This simplifies to 4.29 B km