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QUESTION

What is the Mechanism of Action of tricyclic antidepressants?

 What is the Mechanism of Action of tricyclic antidepressants?

A- Potentiate effects biogenic amines by inhibiting reuptake of norepi and serotonin thus making more available in the synaptic space

B- Forms a stabe, irreversible complex with MAO to prevent demaination of monoamines.

C- Selectively block the reuptake of serotonin and thus enhance serotogenic activity.

D- Converts to dopamine by dopa decarboxylase enzyme to replenish stores in the basal ganglia

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