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What is the Mechanism of Action of tricyclic antidepressants?
What is the Mechanism of Action of tricyclic antidepressants?
A- Potentiate effects biogenic amines by inhibiting reuptake of norepi and serotonin thus making more available in the synaptic space
B- Forms a stabe, irreversible complex with MAO to prevent demaination of monoamines.
C- Selectively block the reuptake of serotonin and thus enhance serotogenic activity.
D- Converts to dopamine by dopa decarboxylase enzyme to replenish stores in the basal ganglia