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What is the mechanism of Synthesis of Zyban (Wellbutrin, Bupropion). In this experiment zyban was synthesized from propiophenone through an acid...
What is the mechanism of Synthesis of Zyban (Wellbutrin, Bupropion). In this experiment zyban was synthesized from propiophenone through an acid catalyzed bromination. The brominated product then underwent a substitution, losing a bromine and gaining a tert-butylamine, to form the Zyban free base. 2M acetyl chloride/isopropyl alcohol was then added to the free base to form Zyban in the presence of HCL salt. And what would be the theoretical yield