When patients who are receiving glucocorticoid therapy (for example, with prednisone) need to stop taking it, the doctor will prescribe a series of

When patients who are receiving glucocorticoid therapy (for example, with prednisone) need to stop taking it, the doctor will prescribe a series of doses of tapering size to gradually lower the dose rather than suddenly stop it. Explain this dosage strategy in terms of the negative feedback control of cortisol secretion and receptor function in hormonal pathways