Which drug is likely to be the most profitable for its producer (in terms of average "per-drug" profit)?

Which drug is likely to be the most profitable for its producer (in terms of average "per-drug" profit)?

The drug that was introduced in the market 1 year ago.

The drug that was introduced in the market 2 years ago.

The drug that was introduced in the market 3 years ago.

The drug that was introduced in the market 10 years ago.

The drug that was introduced in the market 15 years ago.