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Which of the following statements concerning potassium channel openers is true?
Which of the following statements concerning potassium channel openers is true?
a) These agents decrease transmembrane calcium current associated in a smooth muscle with long-lasting relaxation and in a cardiac muscle with a reduction in contractility
b) These agents has a moderate reflex and vascular dilative action caused by the stimulation of sensitive nerve endings
c) Beneficial effects of these agents are related primarily to their hemodynamic effects - decreased heart rate, blood pressure, and contractility - which decrease myocardial oxygen requirements at rest and during exercise
d) These agents increase the permeability of K channels, probably ATP-dependent K channels, that results in stabilizing the membrane potential of excitable cells near the resting potential
