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Write 2 page essay on the topic I am not sure ( just follow the guideline ).Ultimately, a new double helix structure consisting of the old and new daughter strand develops (Mott & Berger, 2007).The fo
Write 2 page essay on the topic I am not sure ( just follow the guideline ).
Ultimately, a new double helix structure consisting of the old and new daughter strand develops (Mott & Berger, 2007).
The formation of the replication fork is necessary for DNA replication. The replication fork is the structure formed when a DNA double helix opens up to facilitate this process. Replication starts at sites referred to as origins of replication where nucleotides are attached to the newly growing strand. It is noteworthy that DNA replication occurs in both directions of the bubble. hence, making the replication process fast (Mott & Berger, 2007).
The initiation phase is the first stage of DNA replication. During this state, the DNA double helix structure unwinds to expose each complementary strand. Specialized enzymes and protein complexes act in combination, to facilitate the process. At first, helicases are used to unwind the double helix structure. After the unwinding process, protein complexes attach to each strand for the incorporation of new nucleotide bases. DNA polymerase is responsible for the biosynthesis of new strands (Mott & Berger, 2007).
The elongation phase is the next step after the initiation phase. During this stage, new daughter strands are copied from the template strand and the process is facilitated by the replication mechanism. The enzyme DNA polymerase is responsible for this elongation process of progressing along the template strand, as new nucleotide bases join up to form new daughter strands. It is noteworthy that DNA replication takes place in the 5’ to 3’ direction. The synthesis of new daughter strands requires an RNA primer, which is synthesized by the primase enzyme. The primer has a 3’ end where the first nucleotide is added with the aid of DNA polymerase. Ultimately, the RNA primer is replaced by DNA molecules when synthesis of the daughter strand is complete (Parkhomchuk et al.,
