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QUESTION

. A 32 y/o woman is diagnosed with hashimoto thyroiditis. Which statement below best describes the pathogenesis of this disease?

. A 32 y/o woman is diagnosed with hashimoto thyroiditis. Which statement below best describes the pathogenesis of this disease?

A. autoantibody thyroid stimulating immunoglobulin (TSI) binds to thyroid stimulating hormone

B. thyroid antigen triggered by a viral infection leads to stimulation of cytotoxic T lymphocytes damage of follicular cells

C. Deficiency of the iodine transport into thyrocytes resulting in defective hormone synthesis

D. autoantibodies against thyroglobulin and thyroid peroxidase with T-cell mediated apoptosis of thyrocytes

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