1)First Question I have is: ______ is released from tumor cells to activate______ cells during the first steps of angiogenesis. PDGF, endothelial!...

1)First Question I have is:

______ is released from tumor cells to activate______ cells during the first steps of angiogenesis.

a. PDGF, endothelial!

b. VEGF, basement membrane

c. VEGF, endothelial!

d. PDGF, basement membrane

e. EGF, endothelial

2) Next Question is:

Almost every cell in the body can become malignant except:

a. epithelial cells b. osteocytes c. erythrocytes d. muscle cells! e. leukocytes

3) The next question is:

A 23-year-old woman is seen for a lump in her

breast that she palpated on self breast

examination. History reveals that her mother and

her aunt both had breast and ovarian cancer.

Given this presentation, you suspect the patient

may have a mutation in which of the following

genes?

a. BRCA1 b. Ras c. Bcl-2 d. p53 e. Rb

4) the next question is:

The functions which have been identified for the

proteins expressed by cellular proto-oncogenes

include all of the following except:

a. growth factor receptor

b. enzyme involved in DNA mismatch repair

c. transcription factor

d. component of a signal transduction pathway!

e. growth factor

5)  The next Question is:

Human papilloma virus enhances cell division by

a. Rb gene activation

b. mutation of Rb gene

c. phosphorylation of Rb protein

d. E2F inactivation! e. none of the above

6) The next question is:

Which of the following is known to increase the risk

of cancer?

a. Helicobacter pylori

b. Epstein-Barr virus

c. Hepatitis B

d. Human immunodeficiency virus

e. all of the above

f. none of the above