A few Comments about Assignment q8 8. Structural chromosomal abnormalities are the single most common cause of pregnancy loss. A phenotypically...

8. Structural chromosomal abnormalities are the single most common cause of pregnancy loss. A phenotypically normal female carries structural variants on both chromosomes 1 and 9. She has suffered five consecutive miscarriages. Cytological study of her periphereal blood revealed 46, XX inv (1) (p32 q34) in all her cells and inversion (9) (p12q12) in 30% of the studied cells. It is likely that the chromosome 1 abnormality is the cause of the woman’s recurrent miscarriages.a)