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QUESTION

A part of the DNA sequence of normal hemoglobin and sickle cell hemoglobin are shown below.

A part of the DNA sequence of normal hemoglobin and sickle cell hemoglobin are shown below. Using your knowledge of transcription and translation, determine the mRNA and amino acid sequence for both normal and sickle cell haemoglobin DNA.      

Normal hemoglobin DNA                         C A C G T G G A C T G A G G A C T C C T C T T C

Sickle cell hemoglobin DNA                     C A C G T G G A C T G A G G A C A C C T C T T C

Comment on the difference between the amino acid sequences obtained and state if this difference would affect the role of haemoglobin as an oxygen carrying protein.

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