Create a 10 pages page paper that discusses diabetes in uae. This study aims to identify patients with Type 2 Diabetes who have also developed cardiovascular disease (myocardial infarction) to measure

Create a 10 pages page paper that discusses diabetes in uae. This study aims to identify patients with Type 2 Diabetes who have also developed cardiovascular disease (myocardial infarction) to measure genetic variation related to T2D with CVD on an Arab population sample in UAE using state-of-the-art technology in genome field. genome-wide Single Nucleotide Polymorphism (SNP) arrays. Our long term goal is to utilize the outcome of the study in the individualization of drug therapy and the diagnosis of T2D with CVD bases on the genetic profile of patients from the Arab Population. This would result in substantial improvements in the quality of life of the affected individuals and a reduction in healthcare costs. Identification of target genes may also lead to the development of novel therapeutic modalities. Furthermore, the characteristics of the Arabic population make them ideal for the genome-wide study of diabetes, a complex, polygenic, multifactorial disorder.

It is hoped that this proposed study will pave the way in identifying susceptibility genes for Type 2 Diabetes with CVD in the UAE population moreover. It will assess if genetic profiling could be used successfully to identify high-risk individuals, this would result in substantial benefits to both individuals and society. Moreover, targeting preventive measures towards individuals with high-risk genotypes could delay the onset of disease, slow its progression, and reduce the ultimate severity of the condition. Finally, this study will lead to substantial improvements in quality of life for affected individuals and a reduction in healthcare costs, and also the identification of target genes might also lead to the development of novel therapeutic modalities.

Dr. Nicolas Christoforou is a molecular-cell biologist and an academician at KUSTER and will, he will avail essential tools in all aspects of molecular biology. He will also provide training and supervision to interns. Dr. Christoforou will dedicate 0.8 calendar months, approximately 8% of his time supervising the project.