How do I work through this problem step by step?

How do I work through this problem step by step? I have access to R-studio

Nitrites are often added to meat products as preservatives. In a study of the effect of these chemicals on bacteria, the rate of uptake of a radio-labeled amino acid was measured for a number of cultures of bacteria, some growing in a medium to which nitrites had been added. Here are the summary statistics from this study.

Carry out a test of the research hypothesis that nitrites decrease amino acid uptake at the 2% significance level.