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the addition of exogenous leptin, at concentrations found in obese patients, induces significant morphological changes in DC.
the addition of exogenous leptin, at concentrations found in obese patients, induces significant morphological changes in DC. The number, length, and diameter of dendrites/llamelopodia are dramatically increases upon treatment of leptin (control experiments verify that the changes are specifically leptin-induced). Design two experimental approaches that would determine which signaling pathway is specifically responsible for this morphological change