The serine protease mechanism has a conserved catalytic triad of asp-his-ser. the specificity of the different serine proteases is governed by the specificity pocket. a. when asp102 is mutated to asn

The serine protease mechanism has a conserved catalytic triad of asp-his-ser. the specificity of the different serine proteases is governed by the specificity pocket.

a. when asp102 is mutated to asn in chymotrypsin, the resulting enzyme has only 1/10,000 of the wild-type enzyme. using what you know of the serine protease mechanism, offer an explanation