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Write 4 page essay on the topic Case report of SLE patinent presenting with erythema nodosum.This patient presented with lupus panniculitis which is a type of rash rarely seen in presenting in patient
Write 4 page essay on the topic Case report of SLE patinent presenting with erythema nodosum.
This patient presented with lupus panniculitis which is a type of rash rarely seen in presenting in patients with SLE and it requires clinical and pathologic knowledge to diagnose. The treatment for this condition can be done with a combination regimen using steroids and another drug, which in this case is Plaquenil. But sometimes this type of treatment would leave hyper pigmentations and scars on the affected skin area after resolution of symptoms.
Lupus panniculitis which is a variant of erythema nodosum or lupus erythematosus has close resemblance clinically and can only be differentiated histopathologically. This is a rare disease which occurs as a separate entity or rarely along with systemic lupus erythematosus. In most cases, it is a disease of women between ages thirty to sixty (Jajic et. al. 29).
This presentation is rare and there are no reports that talk about its incidence or prevalence (Jacyk 258). LEP is an uncommon variant in the clinico-pathological spectrum of lupus erythematosus (erythema nodosum in SLE) characterized by chronic inflammation and hyaline necrosis of subcutaneous tissue (Koley et. al 118). Lupus panniculitis occurs in two to five per cent of SLE patients. Conversely, 10 to 15% of the patients with this disease as well can have or develop SLE. Lupus panniculitis was seen in six out of 228 DLE (Discoid Lupus Erythematosus) patients (Patel and Marfatia 99).
Lupus panniculitis or Lupus erythematosus profundus (LEP) affects the deep corium of the skin and the subcutaneous tissues are mainly involved. This type of panniculitis differs from other panniculitis by its distribution and clinical changes. Usually these lesions develop mostly on proximal parts of the upper extremities, trunks, face and head. They rarely appear on the lower extremities (Jajic et. al. 31) which were seen in the following case report.
A 36 year old female from Saudi presented with
