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I need help creating a thesis and an outline on Biological Basis of Post-Traumatic Stress. Prepare this assignment according to the guidelines found in the APA Style Guide. An abstract is required.

I need help creating a thesis and an outline on Biological Basis of Post-Traumatic Stress. Prepare this assignment according to the guidelines found in the APA Style Guide. An abstract is required. The abnormality seen in individuals with stress can be observed and measured on all major systems of the body including the neural system, endocrine system and the immune system. The Hypothalamic-Pituitary-Adrenal (HPA) axis plays a key regulatory function in the body, which controls all three systems mentioned above. Cortisol is a major hormone of the HPA axis and is the primary stress hormone in the body. Disturbance of glutamatergic, serotonergic, and adrenergic systems is also an important cause of the structural and functional abnormalities which can give stress. The immune system is mutually regulated by the neural and endocrine systems and can also be affected by PTS. PTS often co-occurs with various inflammatory diseases, likely due to HPA axis dysregulation affecting the immune system (Tucker et al., 2004). An increasing body of evidence indicates that posttraumatic stress is associated with major forms of cardiovascular disease including those attributed to atherosclerosis such as coronary heart disease and thromboembolic stroke. Persons with PTS have also been reported to be more likely to have hypertension, hyperlipidemia, obesity, which can precipitate to cardiovascular diseases (McFarlane, 2010).

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