1. What are the role of mast cells? 2. What is the role of histamine? 3. What are the steps of phagocytosis? Explain each step. 3. What causes the edema that occurs during the inflammat

* **** *** *** role of **** ************* ***** **** an ********* role ** ****** *** ******** immunity **** ***** ********* ******* antigens ** ******* to ********* ******** ** *********** with ***** on *** **** **** *********** cells *** involved ** *** regulation ** ******* ** ************* ********* ********* ************ angiogenesis bacterial and ******** *********** In ******** **** ***** regulate ********* ** **** **** ***** **** ** dendritic cells *********** * ***** * ***** fibroblasts *********** *********** ***** and ********** cells ***** **** ***** ******** *** ******* multi-potent molecules **** ** ********* ********* prostanoids ************ ******* *** **** ********* ********** *** growth ******* they **** *** capacity ** ** involved ** ********** the ********* ** **** ****** *** ******* *** ** the ****** ******* functions ** the **** **** ** *** role ** ******** and ********* *********** **** cells **** **** * *********** **** in the regulation ** **** ****** remodeling and ******* *************** **** ** the **** ** *********** *********** * ********** ***** **** ****** temporary rapid ************ ofthe ***** vessel ***** and ******** ** *** postcapillary venules **** ** *********** in ********* ***** flow **** *** **************** ********* **** causesincreased vascular ************ resulting **** retraction of *********** *********** *** capillaries" ******** ************ ***** ********* ***** a verycrucial **** in *** ************ ******** *** in ******* *** human *********** for survival **** ****** ** ********* ******* ** receptors ******** animportant negative-feedback mechanism that stops ************* **** ** *********** histamine ******** ******* of additional ********* ** interacting ****** ********* ** *** **** cells ********* **** *** ****** control of ********* response through ** ********* ** **** ***** of *** ****** ************* ********* ******** ** ********* ** enhancement ** *** ******************* of ***** ******* **** ** ********** *********** ****** ** ****************** ***** ******** eosinophils **** sites of allergic inflammatory ************ ******** **** **** ********* out of *** ************ ***** * ******* **** ***** "Cells ** **** *** ****** *** adaptive ****** ********* *********** ** histamine" (Barcik ********** ***** ************* ****** **** *** the steps ** ************* Explain each ************* to ******* *** Huether ***** * 211) ***** *** **** ***** ******** ** *** ************ ******** ************ ********** ****** *** *********** ********** *** * type ** **** *********** eosinophil basophil monocyte/macrophage) that can ******* *** ******* of ************* ** Opsonization:(non-specific ************ ***** *** ********* attracted *** ******* ** the ****** ***** *********** ******* happens ** ******** ** ********** ********* ********* ***** ******* enhances both recognition and ********* ** ********* with *** ********* Opsonins ******** as *** **** ******* phagocyte *** target cell ********** **** an **** ******** **** *** *** ***** facilitate the ************ processStep ** Engulfment ******************* where *** ************* is ingested **** the **** *** ***** * phagocytic ******* or ********* (membrane bound ******* **** ******** *** ************* *** ** *** ****** *** ********** *** ************* plasma ******** ** ******** ***** ***** * role in the next ***** ** ********** ** ************ *** formation ** the phagosome ********* ***** ****** *** cell **** **** *** phagosome *** ***** ************ ******** creating * ************* ******* ********* granules: ************ molecules including: myeloperoxidase ******** defensins **** ********** elastase Secondary ********* ********* **** *** bactericidal *** *** ******** ** ********** ****** ******** ******** *********** lactoferrin *** ***** ************* 4: ************ after ******** ** the ******** *** ******** inside the phagolysosome the ************* ** **** ****** *** ******** *** nutrients **** the **** *** *** are absorbed *** ********* ***** ******** *** ******* **** the **** ******* ********** The *** ways **** ** ********* is through ** oxygen ********* *** oxygen independent ************* **** causes *** ***** **** ****** ****** *** ************ ********* ***** ********* of *** ****** protein ****** **** ********** ************** *** *********** ** *********** *** macrophages?5 What is ** ******** How **** ** antigen ***** * *********** ******* is * molecule ******** proteins) **** *** the ******* to react to ********** ** * and * ***** **** antigens ** ********* *** *********** or induce responses **** ******* ********** ** ********** T ***** ******** &Huether 2014 p ****** order *** ******** to ******** appropriately * ******* of *** ********* **** ** recognized by *** **** ** specific ********* ** * ********** ******** *** also be ********** ** *** **** ** ********** The **** ** *** antigen **** ** ********** *** *********** ** an epitope (McCance ************ **** * 228)Antigens cause * ******** *** ******* ** *** ******* ** autoimmune ********* and diseases ******* going **** ** ******* **** ********* **** **** ****** an immune response ** *** form ** an ******** *********** ****** *************** ** designed to create ********* protection ******* ******** *** ******* ** ******* ********** ** which ******** cause * ******** to **** functioning ************* *** immune ****** will ********* and ******* substances **** ******* ******** ********* ********** ** ****** 2018)6 MHC and *** ********* *** ***** ******* **** ********* contain ******** and ** 1 ********* *** alike ******* ******* **** ********** *** plasma membrane byhydrophobic ******* ** the **** of the ** *** ********* How ** surfactant ******** * ******* * provide ****** ************** ***** ******* *** secrete glycoproteins collectins ********** encompasses surfactant ******** A ******* * *** ******* site ** **** ********* reacts **** ********* ********** ** * ***** ** *************** ******** ********** ** ********* * **** ***** of ********** ************** (McCance ************ **** p **** This ********** * *** * collectin ****** ********** *** *********** recognition ** *** microorganism ** *********** ********* macrophage ********** ******* ************ ************ ** *** ****** ** which ***** ******* and ******** ** ************** ******* ******** *** damaged cells ******** ************ 2014)8 **** *** *** ****** ** *** ******* ******** syndrome?Selye ***** *** ******* ********** ******** ***** *** ** * ***** he discovered ** manifestations **** *********** * nonspecific ******** ** injurious ******* *** ******* ********** ******** *** three sequential ****** Stage *** ** the ***** ***** ** ******** ** ***** one the ******* nervous ****** is aroused and *** ******** ******** *** ********* **** ** *** fight or ****** ********** ***** *** ** *** stage ** resistance or ********** During ***** *** ************ *********** ** fight ** ****** ******* ***** three ** *** ***** of exhaustion ** stage three ************ ********** *** *********** ** broken down due ** continuous ****** ***** three ***** *** ***** ** ******* ******** ********** occurs **** stress ********* and ********** ** not ********** ******** &Huether 2014 * 339)9 Differentiate between ******* *** active ******** **** ************** ******** ** **** * person ** ******* to *** ********** for ******* or receives *** ********** ******* *** an ****** response takes ***** ** response ** *** ******** *** **** **** produce ********** ** * ***** ******** ************ ***** ******* ******** ** **** * ***** ******** ******** antibodies ******* *** ******** ** ******* ******* ****** **** ** **** not elicit ** ****** ******** *** *** ******** ******** is only ********* ******** &Huether 2014) 10 **** are ** ****** ************* ****** ***** are * **** ** lymphocyte ** *** ****** immune ****** **** **** the ****** ** ***** and viral ***** by ******* to *** ***** *** ********** ********* *** then ********* cytokines *** ***** ********* **** **** *** target **** *** ** ***** **** inhibitory *** ********** ********* that **** them the ability ** ************* ******* ******** cells ********* ** ***** ****** *** ****** **** ***** ******** ************ 2014 * ******** **** is *** ******* ** *** ************ ********** ******* ** *** ************ ******* is ******** ****** *** form ** assault on *** body ******* ****** ****** ******** injury ** physical affliction This ******** ** ** be * ********* defense ** *** body(McCance ************ 2014) **** *** body ** ******* ***** ** vasodilation to **** with delivery ** white blood ***** ** *** **** ** the injury *** ** **** fight *** any ********** agents **** may ** ****** ** invade *** ****** **** is ****** **************** ********* ******** *** ******* ** T and * ***** ** ********* *** ******* ******* ***** ** *** *********** **** * *** * **** recognize a specific antigen *** *** *** ** *** ***** *********** ultimately **** ** *********** ******** ** ******** This ******* ****** ** *** thymus *** * ***** and **** ****** *** * ***** ***** ****** release *** *********** *** **** the ***** ******* ******* ******* that **** them **** ****** * ** * ***** **** then ******* ** ***** ******** ****** ** *********** *** ******* ******** ******** p ****** What ***** ** *********** *************** **** to play * indirect **** ** *** ******** ** *** body ** ************ which ****** **** the ******** *** ********* **** inhalation to ******* ********* "Fibroblasts *** *** ***** *********** tropocollagen ***** ** *** ********** ********** andground substance ******************* matrix **** ***** the ****** ******* cells *** ****** ** ********** ******* (Yun ***** *** 2015) ***** **** ******** ** ** create *** ************* matrix ***** ** what ********* *** ***** **** ****** ****** *** transfer ** the chemicals that cells **** to one ******* **** ****** **** ****** the cells ** remain ****** **** ************ ****** ** ****** ********** ******* ************* ****** ***** ******** comprise another ******** of ******* Whilst *** **** ********** ********** ** ***** proteins *** those concerned with providing ********** tissue ********* ** is clear that **** **** **** powerful ********* effects ******* *** ******** can influence *** ***** ******** *** state ** ********** ** ************ ***** ** *** ****** ****** ******** indicates **** these signals *** **** **** *********** roles ** ****** of ************ ***** ** ******* ***** and in *** handling of * number ** ********* *** growth factors" ******** ***** ********** & **** ***** ** appears that *********** *** ******** ***** important ******* **** create the ****** ** ***** these ********* ******* travel ******* *** ****** ***** ***** ***** not ** allowed ** properly communicate with one another nor ***** they ** **** to maintain ***** ********* ***** ******** What ****** ******* ** ******* *** ****** care ******* ***** healing is important **** it related to any type ** ***** In **** ****** ***** *********** ** vital *** ******** ******** When * wound does *** progress or heal within *** ****** ** one **** Medicare ******** the wound ******* *** **** *** *** *** **** care services ** supplies ***** *** complex cases where ****** do *** **** due to ******* reason ****** **** a six-step healing ******* ***** are as ******* ***** ********** ************ proliferation *** ********* ************ **************** *** **************** * ***** ******** * * ***** ****** *** ************** ***** there is ***** ***** ******* whichassembly *** remodeling ** *** ******** ****** ***************** ** the wound *** *** *********** of the ************* * &Huether * **** p 1625-1626)Dysfunctional wound healing can ****** ** anytime in the ******* of *** ************** ************* K ************ S 2014 * ********** *** reason ******* ****** ** *** **** *** ************* influenced *** caused ** abnormal ***** ******* **** excessive fibroblast ******** *** ******** ********* during ****** ********** tissue repair ****** ********* has **** ***** ** **** autosomal ********* *** ********* ******** *********** patterns have been reported(McCance * ************ S **** * ********** ******* ****** ** ****** *** ** an ********* between ********** ********* *** connective *********** **** is ***** ** ** **** ******** ** ******* the ********* **** ***** is ****** *** recent ******** has ***** ********** ****** *** less ********* *** **** the ********** ** respond ** ****** *********** **************** K ************ * 2014 * ********** ******* ****** have an increase ** **** *** ******** *** reticular ***** ** keloids *** ************ scars ******** ************ cells ********* ******* of *********** newly ****** ***** ******* *** ******** ************** 2017) ****** ********* synthesis of ******** ** ********** with ************* ****** signaling *** dermal fibroblasts **** **** **** metabolic and ******* ***** There ** ******** expression ** ************ ****** *********** ******** and **************** ****** factor ***************** K &Huether S **** * ************ ***** ******* ****** **** *** ******* ** occur ****** *** ************ *********************** ** defined ** * ***** response ** cellular ****** **** is ****** by ******* heat and **** and **** ****** ** * ********* initiating *** elimination of ******* ****** *** ** ******* ********* *********** **** p34)These *** *** cardinal ***** ** ************ along **** ******** ******* *** ******* *** *** result ** ************ *** increased ***** **** ******* the ******* ******* ******** ************ 2014p213) *** ***** process occurs ** **** order:“First ********** **** *** **** of ********* ** ****** constrict briefly ************ then ****** ****** blood velocity and ********* local blood **** ** *** ******* **** *** ********* **** *** capillary permeability ****** ** ******* ** ****** **** *** ******* ******* ******** ******* ** *** *********** tissue ** ****** ***** ******* ***** ********* in *** **************** ***** more slowly and ******* more ********** ********* ***** **** *** ********** ************* of red ***** at *** **** ** ************ ***** ******* increased ****** and ********** ******** ************ 2014p195)During *** inflammation ******* ******** ***** ***** *********** with **** other *** ********* ***** *** polypeptides released by cells of *** ****** ****** **** regulate ***** ***** **** *** a ***** class ** ******* ********* that ****** *** cell **** ** ******* particularly ** ******** ** ******* substances”(“Inflammation” ******* **** ** the ********** ******** What role does ** ***** What ** its *** result?17 What *** cytokines *** **** ***** do **** play?Cytokines *** **** ********* molecules **** ****** **** to **** ************ ** ****** ********* *** ********* *** movement ** ***** ** *** direction ** ************ ********* and ****** ********* lives ** peptide ******* and ************ ********** *** two main classifications ** ********* *** ************ *** interferons ******** * ******** ************ *** ********* ****** ** *********** and **************** ********* increase the adaptive ****** ******** ** fight ******* ********** ************** *** ***** unknown ********************** *** **** an ***************** ******** and **** ****** the ************ ************ *** ** ************* **** and ****** *** body’s *********** to **** ******* *** infectionPhagocytes and lymphocytes *** ********** ** ***************** reactions ******************* *** *********** *** development of ********** ** *** **** ****** *** ******* the ***** molecule communication of different ***** ******** * **************** **** ***** ******* ***** ********** and control the ************ ****************** cells *** ********* by ********** proteins manufactured by *** interferonsInterferons also ****** ** the *********** ** the ******** immune reaction ******* ***** ******** ** ******** ***** ******** * *************

Click here to download attached files: South-University-NSG5003-week-2-study-guide.docx